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With everything that people deal with to lose weight, diets that do not work, diet pills that won't do what they are likely to, overpriced exercise equipment, simply to name a few. It is no wonder that now the latest idea is to blend prescription medications with the idea that while using combination could have the miraculous results that they can so desperately want and in some cases need. Using two separate drugs to shed pounds can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight reduction and the people who go through it you ought to err along the side of caution and allow FDA do its job and demand some investigation be done so the public recognizes the side effects and dangers of the medications before we drive them. Keep in mind that drug companies have been in business to earn money and that they would say anything to keep people on the medications. Researchers found that participants using this drug for any year, lost weight within a month and have kept the body weight off through the entire 56 weeks in the study. Contrave is often a combination in the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which are made up of several active ingredient, which can make them more efficient and safer. Combo-pilling may be the newest fad or better yet the newest into the future under scrutiny and for that reason it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular may be the fact that by right now there are not any long term prescription slimming capsules that have been approved by the FDA besides orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be approved by the FDA. Seizures are a side effect with Contrave and must not be taken in those with seizure disorders. The drug could also raise blood pressure level and heartrate, and mustn't be used in people who have a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure and heart rate and must 't be used in patients with uncontrolled high hypertension, and also by a person with heart-related and cerebrovascular (circulatory dysfunction impacting your brain) disease. Patients with a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients for the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for smoking cessation. "There were no indications of depression or suicidal thoughts in trial participants," said Fujioka.